Lacking Natural Simplicity

It turns out that if you execute the command xterm-mouse-mode (or evaluate (xterm-mouse-mode 1) in your initialization file) when running Emacs under Screen it allows “non-modified single clicks” to work. Normal mouse functionality is still available by holding the Shift key while clicking. I use the PuTTY ssh client for remote access to various servers, and this works well Emacs in Screen under PuTTY, too.